Scientist, Analytical Development

64 - Quality Control & Analytical Development - Redwood City, CA - Full Time

We are looking for an Analytical Development Scientist possessing depth of knowledge of analytical techniques and instrumentation who will apply their expertise and hands-on skills to:

• provide guidance on analytical methodologies and method development support for the multidisciplinary project teams
• assist with internal protein drug development projects through physicochemical characterization studies and pre-formulation studies, inclusive of CMO/CRO oversight
• develop of assays for characterization and release testing of diagnostic enzymes
• to assess the performance of enzymes as biocatalysts by measuring the conversion of small molecule substrates into products

Responsibilities include:

• Ability to independently develop strategies to deconvolute complex analytical problems and execute them to provide robust solutions 
• Independently design and carry out method development & validation following ICH Q2
• Protein assay development (HPLC, LCMS, electrophoretic and spectrophotometric assays, ELISA, SDS-PAGE, Western-Blot)
• Pre-formulation and physicochemical characterization studies
• CMO/CRO oversight
• Troubleshoot analytical instrumentation, including HPLC.
• Maintain knowledge of new emerging techniques and equipment to add to the knowledge pool of the group and provide input for all ongoing development programs and instrument acquisitions.
• Development guidance to analysts in the group.
• LCMS  and/or small molecule method development experience in GMP environment a plus

• Perform analyses as necessary to support the project teams

Job Requirements

• PhD with a minimum of 5 years, MS with 10 years, BS with 15 years in Analytical Chemistry or Analytical Biochemistry required
• Thorough knowledge of protein characterization/development (2-5 years of biotech/pharma industry experience)
• Demonstrated expertize in the independent design and execution of analytical development projects
• Experience in a GMP environment and working knowledge of ICH guidelines
• Extensive HPLC experience
• Chromatography experience
• Experience with biocatalysts and enzyme based assays is preferred
• Working knowledge of statistical tools for data analysis
• Proficient computer skills and experience with commonly used analytical  laboratory software
• Good oral communication and written skills
• Ability to mentor and train junior staff
• Demonstrated ability to work effectively in cross-functional teams
• Strong focus on quality and attention to detail


The position comes with a competitive compensation and benefits package, including paid company holidays, paid time off, health benefits, 401k match, and much more.  For more information about our plans for the future, and to be considered for this career opportunity, please visit


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