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Scientist, Process Chemistry & Chemical Development

At Codexis, we are creating sustainable chemicals, pharmaceutical processes, and renewable ingredients that make industry more efficient, productive and profitable. Industrial biotechnology from Codexis re-engineers enzymes and microorganisms – nature’s catalysts – and puts them to work to solve real global challenges for the world’s largest companies. 


Responsibilities include:

Codexis is seeking an exceptional chemist to join our team.  The position reports to the Director, Process Chemistry,   and will work as part of a high-performing team to achieve project deliverables including:

  1. Fosters an environment of the highest levels of laboratory and site safety.
  2. Interacts with Analytical Biochemists and Molecular Biologists in characterizing and optimizing enzyme and process parameters.  
  3. Designs, establishes and validates scalable and safe chemical processes leadings to pharmaceutical intermediates, API’s and other value added chemical products. 
  4. Designs and carries out experiments in medium to high throughput.
  5. Synthesis of organic substrates, intermediates and products. 
  6. Supervises and mentors the work of research assistants if required.
  7. Proper record keeping and data analysis.
  8. Preparation of documentation for tech transfer of chemical process.


  1. The candidate should have extensive knowledge of either organic chemistry (chirality, catalysis, kinetics, analytical, synthesis) or synthetic biochemistry (enzyme kinetics, enzyme inhibition) in addition to strong organic chemistry skills (chirality, synthesis and purification).  
  2. Knowledge and use of analytical instrumentation (HPLC, GC, MS). 
  3. Master’s degree with 3 years working experience or PhD degree in Chemistry, Biochemistry, or related fields is required.
  4. Candidates with relevant full time industrial experience within R&D or manufacturing industries are preferred.
  5. Understanding of: process chemistry (reaction up-scaling, safety, and downstream processing); design of experiments (DoE) implementation; molecular and directed evolution are useful but not essential.
  6. Other requirements: ability to work in highly parallel manner, ability to work in a multi-disciplinary team; critical thinking and keen attention to detail; ability to plan, prioritize responsibilities and multi-task; excellent housekeeping and safety practices; excellent communication, documentation and organization skills.


The position comes with a competitive compensation and benefits package, including paid company holidays, paid time off, health benefits, 401k match, and much more.  For more information about our plans for the future, and to be considered for this career opportunity, please visit



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